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Topical cyclosporin as an alternative treatment for vision threatening blepharokeratoconjunctivitis: a case report
Ismail AS, Taharin R, Embong Z
International Medical Case Reports Journal , 2012, DOI: http://dx.doi.org/10.2147/IMCRJ.S29960
Abstract: pical cyclosporin as an alternative treatment for vision threatening blepharokeratoconjunctivitis: a case report Case report (1235) Total Article Views Authors: Ismail AS, Taharin R, Embong Z Published Date June 2012 Volume 2012:5 Pages 33 - 37 DOI: http://dx.doi.org/10.2147/IMCRJ.S29960 Received: 15 January 2012 Accepted: 09 March 2012 Published: 27 June 2012 Abdul-Salim Ismail,1,2 Rohana Taharin,2 Zunaina Embong1 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, 2Department of Ophthalmology, Hospital Pulau Pinang, Jalan Resindensi, Pulau Pinang, Malaysia Abstract: Here, a case of vision threatening blepharokeratoconjunctivitis that responded well to topical cyclosporin is reported. A 9-year-old Malay girl with a history of bilateral blepharokeratoconjunctivitis was regularly treated with lid scrubbing using diluted baby shampoo, fusidic acid gel, and topical steroids as well as an intermittent course of oral doxycycline for the past year. She developed acute onset bilateral eye redness associated with poor vision in her right eye. Both eyes showed marked diffuse hyperemic conjunctiva with corneal vascularization. The presence of corneal vascularization obscured the visual axis in the right eye. The condition did not improve with regular intensive lid hygiene using diluted baby shampoo, fusidic acid gel, and topical steroids. She was started on topical cyclosporin A 0.5% every 6 hours. There was a dramatic regression of corneal vascularization after 3 days on topical cyclosporin, with marked improvement in visual acuity. This is a single case in which cyclosporin improved the status of the ocular surface. A large cohort study is required to justify its effectiveness in treating blepharokeratoconjunctivitis and to test its potential as an alternative immunosuppressive agent in comparison to conventional corticosteroids.
Topical cyclosporin as an alternative treatment for vision threatening blepharokeratoconjunctivitis: a case report
Ismail AS,Taharin R,Embong Z
International Medical Case Reports Journal , 2012,
Abstract: Abdul-Salim Ismail,1,2 Rohana Taharin,2 Zunaina Embong11Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, 2Department of Ophthalmology, Hospital Pulau Pinang, Jalan Resindensi, Pulau Pinang, MalaysiaAbstract: Here, a case of vision threatening blepharokeratoconjunctivitis that responded well to topical cyclosporin is reported. A 9-year-old Malay girl with a history of bilateral blepharokeratoconjunctivitis was regularly treated with lid scrubbing using diluted baby shampoo, fusidic acid gel, and topical steroids as well as an intermittent course of oral doxycycline for the past year. She developed acute onset bilateral eye redness associated with poor vision in her right eye. Both eyes showed marked diffuse hyperemic conjunctiva with corneal vascularization. The presence of corneal vascularization obscured the visual axis in the right eye. The condition did not improve with regular intensive lid hygiene using diluted baby shampoo, fusidic acid gel, and topical steroids. She was started on topical cyclosporin A 0.5% every 6 hours. There was a dramatic regression of corneal vascularization after 3 days on topical cyclosporin, with marked improvement in visual acuity. This is a single case in which cyclosporin improved the status of the ocular surface. A large cohort study is required to justify its effectiveness in treating blepharokeratoconjunctivitis and to test its potential as an alternative immunosuppressive agent in comparison to conventional corticosteroids.Keywords: blepharokeratoconjunctivitis, cyclosporin
Power Aware Routing Protocol (PARP) for Wireless Sensor Networks  [PDF]
R. Prema, R. Rangarajan
Wireless Sensor Network (WSN) , 2012, DOI: 10.4236/wsn.2012.45019
Abstract: Several wireless sensor network applications ought to decide the intrinsic variance between energy efficient communication and the requirement to attain preferred quality of service (QoS) such as packet delivery ratio, delay and to reduce the power consumption of wireless sensor nodes. In order to address this challenge, we propose the Power Aware Routing Protocol (PARP), which attains application-specified communication delays at low energy cost by dynamically adapting transmission power and routing decisions. Extensive simulation results prove that the proposed PARP attains better QoS and reduced power consumption.
An Innovative Low Cost EM Pollution Measurement System  [PDF]
R. Sittalatchoumy, R. Seetharaman
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.78176
Abstract: Mobile phones and other electronic devices are emitting radiations that will provide harmful effects to the human health. In order to measure the radiation, an innovative low cost measurement system is proposed in this paper. The ideology is to simplify the circuit’s value by converting a voltage detecting circuit to a field detecting circuit by finding an optimum resistance on trial and error basis. The requirement for a trial and error technique is to not allow too high or too low resistance which can be either short or open, resulting provides more damage to the circuit.
Ant Lion Optimization Approach for Load Frequency Control of Multi-Area Interconnected Power Systems  [PDF]
R. Satheeshkumar, R. Shivakumar
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.79206
Abstract: This work proposes a novel nature-inspired algorithm called Ant Lion Optimizer (ALO). The ALO algorithm mimics the search mechanism of antlions in nature. A time domain based objective function is established to tune the parameters of the PI controller based LFC, which is solved by the proposed ALO algorithm to reach the most convenient solutions. A three-area interconnected power system is investigated as a test system under various loading conditions to confirm the effectiveness of the suggested algorithm. Simulation results are given to show the enhanced performance of the developed ALO algorithm based controllers in comparison with Genetic Algorithm (GA), Particle Swarm Optimization (PSO), Bat Algorithm (BAT) and conventional PI controller. These results represent that the proposed BAT algorithm tuned PI controller offers better performance over other soft computing algorithms in conditions of settling times and several performance indices.
Obtaining Optimal Solution by Using Very Good Non-Basic Feasible Solution of the Transportation and Linear Programming Problem  [PDF]
R. R. K. Sharma
American Journal of Operations Research (AJOR) , 2017, DOI: 10.4236/ajor.2017.75021
Abstract: For the transportation problem, Sharma and Sharma [1] have given a very computationally efficient heuristic (runs in O(c*n2) time) to give very good dual solution to transportation problem. Sharma and Prasad [2] have given an efficient heuristic (complexity O(n3) procedure to give a very good primal solution (that is generally non-basic feasible solution) to transportation problem by using the very good dual solution given by Sharma and Sharma [2]. In this paper we use the solution given by Sharma and Prasad [2] to get a very good Basic Feasible Solution to transportation problem, so that network simplex (worst case complexity (O(n3*(log(n))) can be used to reach the optimal solution to transportation problem. In the second part of this paper, we give a simple heuristic procedure to get a very good BFS to linear programming problem from the solution given by Karmarkar [3] (that generally produces a very good non-basic feasible solution in polynomial time (O(n5.5)). We give a procedure to obtain a good BFS for LP by starting from the solution given by Karmarkar [3]. We note that this procedure (given here) is significantly different from the procedure given in [4].
The Meaning of the Verb igrati
R.
- , 1953,
Abstract: Hr?ak ID: 5132
Zna?enje glagola igrati
R.
- , 1953,
Abstract: Hr?ak ID: 5132
Nekoliko misli o potro?nji riba
r.
- , 1951,
Abstract: Hr?ak ID: 15951
Dasen Vrsalovi? - Istra?ivanja i za?tita podmorskih arheolo?kih spomenika u SR Hrvatskoj
R., ?.
- , 1975,
Abstract: Hr?ak ID: 14666
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